Melkersson-Rosenthal syndrome in mainland China

نویسندگان

  • Jian-Jun Tang
  • Xiang Shen
  • Jia-Jia Xiao
  • Xiao-Ping Wang
چکیده

Melkersson-Rosenthal syndrome (MRS) is a rare disease with unclear etiology. The clinical manifestations of MRS are characterized by swelling face and lips, peripheral facial paralysis, and fissured tongue. We summarized 69 patients with Melkersson-Rosenthal syndrome in mainland China by searching for PubMed, and Chinese main electronic databases including Chinese National Knowledge Infrastructure Databases (CNKI) and Wanfang. This disease could occur at any age, including teenagers and aged person. 75.4% of patients with typical MRS triad symptoms, while the others only with one or two initial symptoms. Cheilitis granulomatosa is also a type of MRS. No standard diagnostic criteria has been issued to date, and biopsy is generally needed to make a definite diagnosis. Immunosuppressive therapy is of some efficacy in treating MRS; however, no specific treatment has been identified to treat MRS.

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تاریخ انتشار 2016